“I’m delighted there was an explanation that didn’t involve fraud,” Dr. Gearhart said.
Within Discredited Stem Cell Research, a True Scientific First
By NICHOLAS WADE
The world of stem cell research was set reeling two years ago when its most successful practitioner, the Korean scientist Hwang Woo Suk, was found to have fabricated much of his work. But according to a new post-mortem of his research, he did achieve a scientific first, though not the one he claimed.
Dr. Hwang said he had derived embryonic stem cells from the adult cells of a patient, but the claim was discredited after parts of his research were found to have been faked. A team of Boston scientists has now re-examined stocks of Dr. Hwang’s purported embryonic stem cells and arrived at a surprising conclusion: His embryonic stem cells were the product of parthenogenesis, or virgin birth, meaning they were derived from an unfertilized egg.
A team led by Kitai Kim and George Q. Daley of Children’s Hospital Boston reports this conclusion today in the journal Cell Stem Cell.
Embryonic stem cells derived through parthenogenesis cannot develop normally, so they are free of ethical objections. The cells could perhaps help treat degenerative diseases in women capable of supplying eggs, should effective treatments ever be developed.
Other researchers have since developed embryonic stem cells from parthenogenetic eggs, but Dr. Hwang’s team would have been the first to do so had its members recognized what they had done.
“It could have been a seminal finding if they hadn’t had their blinders on,” said Kent E. Vrana, an expert on parthenogenesis at Pennsylvania State University.
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